Autosampler sample and sample rack identification

ABSTRACT

A sample identification system for an automated sampling device is described. A system embodiment includes, but is not limited to, a sample holder having a plurality of apertures configured to receive a plurality of sample vessels therein, the sample holder having one or more corresponding sample holder identifiers positioned proximate to the sample holder; and an identifier capture device configured to detect the one or more sample holder identifiers positioned proximate to the sample holder and generate a data signal in response thereto, the data signal corresponding to at least an orientation of the sample holder relative to a surface on which the sample holder is positioned.

CROSS-REFERENCE TO RELATED APPLICATIONS

The present application claims the benefit under 35 U.S.C. § 119(e) ofU.S. Provisional Application Ser. No. 62/201,725, filed Aug. 6, 2015,and titled “AUTOSAMPLER SAMPLE RACK IDENTIFICATION,” and of U.S.Provisional Application Ser. No. 62/201,722, filed Aug. 6, 2015, andtitled “AUTOMATIC DETECTION OF EXPIRED STANDARD SOLUTIONS,” each ofwhich is herein incorporated by reference in its entirety.

BACKGROUND

In many laboratory settings, it is often necessary to analyze a largenumber of chemical or biochemical samples at one time. In order tostream-line such processes, the manipulation of samples has beenmechanized. Such mechanized sampling is commonly referred to asautosampling and is performed using an automated sampling device orautosampler.

SUMMARY

A sample identification system for an automated sampling device isdescribed. A system embodiment includes, but is not limited to, a sampleholder having a plurality of apertures configured to receive a pluralityof sample vessels therein, the sample holder having one or morecorresponding sample holder identifiers positioned proximate to thesample holder; and an identifier capture device configured to detect theone or more sample holder identifiers positioned proximate to the sampleholder and generate a data signal in response thereto, the data signalcorresponding to at least an orientation of the sample holder relativeto a surface on which the sample holder is positioned.

A method embodiment includes, but is not limited to, detecting a sampleholder identifier positioned on a sample holder, the sample holderhaving a plurality of apertures configured to receive a plurality ofsample vessels therein; and determining an orientation of the sampleholder based upon the sample holder identifier detected, the orientationof the sample holder being relative to a surface on which the sampleholder is positioned.

This Summary is provided to introduce a selection of concepts in asimplified form that are further described below in the DetailedDescription. This Summary is not intended to identify key features oressential features of the claimed subject matter, nor is it intended tobe used as an aid in determining the scope of the claimed subjectmatter.

FIGURES

The Detailed Description is described with reference to the accompanyingfigures. The use of the same reference numbers in different instances inthe description and the figures may indicate similar or identical items.

FIG. 1 is an isometric view illustrating an automated sampling ordispensing device in accordance with example implementations of thepresent disclosure.

FIG. 2A is a partial isometric view illustrating an automated samplingor dispensing device in accordance with example implementations of thepresent disclosure, where a center slot in the support surface ispresent allowing the sample arm assembly to be connected with the driveassembly.

FIG. 2B is a partial isometric view illustrating an automated samplingor dispensing device in accordance with example implementations of thepresent disclosure, where a raised slot on the support surface ispresent to attach the sample arm assembly to the drive assembly.

FIG. 3 is an exploded view of the automated sampling or dispensingdevice shown in FIG. 1, further illustrating components of the device.

FIG. 4A is an isometric view illustrating an automated sampling ordispensing device in accordance with example implementations of thepresent disclosure where multiple sampling arm assemblies and driveassemblies are mounted to the top of the support surface of theautomated sampling or dispensing device.

FIG. 4B is a plan view illustrating an automated sampling or dispensingdevice in accordance with example implementations of the presentdisclosure, where multiple sample arm assemblies and rinse stations arepresent on one support surface.

FIG. 5 is an isometric view illustrating an automated sampling ordispensing device in accordance with example implementations of thepresent disclosure, where the support surface of the automatic samplingor dispensing device is provided with more than one plane.

FIG. 6 is an isometric view of the automated sampling or dispensingdevice shown in FIG. 1, further illustrating the drive assembly.

FIG. 7 is a partial isometric view of the drive assembly shown in FIG.6, further illustrating components of the drive assembly.

FIG. 8 is a partial isometric view illustrating a sample arm assemblyfor an automated sampling or dispensing device in accordance withexample implementations of the present disclosure.

FIG. 9A is a plan view illustrating a support surface for use with anautomated sampling or dispensing device, where the support surfaceincludes a slot and has a footprint in accordance with exampleimplementations of the present disclosure.

FIG. 9B is a plan view illustrating a support surface for use with anautomated sampling or dispensing device, in accordance with exampleimplementations of the present disclosure.

FIG. 10 is an isometric view illustrating an automated sampling ordispensing device in accordance with example implementations of thepresent disclosure, where the device includes a shroud.

FIG. 11 is an isometric view illustrating an automated sampling ordispensing device in accordance with example implementations of thepresent disclosure, where the device is contained within a hood.

FIG. 12 is an isometric view illustrating an automated sampling ordispensing enclosure in accordance with example implementations of thepresent disclosure, where the enclosure includes two flexible sheets.

FIG. 13 is a partial front view of the automated sampling or dispensingdevice enclosure as illustrated in FIG. 12, where one of the flexiblesheets of the enclosure is retracted.

FIG. 14 is a front view of the automated sampling or dispensing deviceenclosure as illustrated in FIG. 12, where the mechanism of fastening aflexible side shut is demonstrated.

FIG. 15 is a front view of the automated sampling or dispensing deviceenclosure as illustrated in FIG. 12, where the flexible sheets have beenremoved.

FIG. 16 is an isometric view illustrating an enclosure for a bench topautomated sampling or dispensing device in accordance with exampleimplementations of the present disclosure, where the enclosure includesflexible sheets which are in a closed position.

FIG. 17 is a front view of the enclosure for the bench top automatedsampling or dispensing device as illustrated in FIG. 16, where theflexible sheets are in an open position.

FIG. 18 is an isometric view illustrating an enclosure for an automatedsampling or dispensing device in accordance with example implementationsof the present disclosure, where the enclosure includes a singleflexible front sheet.

FIG. 19 is an isometric view of the enclosure for the automated samplingor dispensing device as illustrated in FIG. 18, where the front sheet isretracted allowing access to the device.

FIG. 20 is a partially exploded isometric view of an automated samplingor dispensing device having a sample identification system in accordancewith example implementations of the present disclosure.

FIG. 21A is an isometric view of the automated sampling or dispensingdevice of FIG. 20.

FIG. 21B is an isometric view of an automated sampling or dispensingdevice having a sample identification system in accordance with exampleimplementations of the present disclosure.

FIG. 21C is an isometric view of the automated sampling or dispensingdevice of FIG. 20 shown in an operating position.

FIG. 22 is a partial side view of an identifier arm assembly in positionbeneath a sample holder having sample vessels with sample identifiers.

FIG. 23A is an isometric view of a sample holder including asubstantially transparent bottom.

FIG. 23B is an isometric view of a sample holder including a first setof apertures configured to hold sample vessels and a second set ofapertures on a bottom portion of the sample holder.

FIG. 24 is a partial side view of an identifier capture device and asample probe, where the identifier capture device is aligned with thesample probe.

FIG. 25 is an isometric view of an identifier arm assembly having anidentifier capture device.

FIG. 26A is a side view of an identifier arm assembly relative to anidentifier capture device for a system, such as the system shown in FIG.20, where the identifier arm assembly is positioned substantiallyperpendicular to the alignment axis, and where the identifier capturedevice is positioned at an angle from perpendicular to the alignmentaxis.

FIG. 26B is a side view of an identifier arm assembly relative to anidentifier capture device for a system, such as the system shown in FIG.20, where the identifier capture device is positioned substantiallyperpendicular to the alignment axis, and where the identifier armassembly is positioned at an angle from perpendicular to the alignmentaxis.

FIG. 27 is a bottom perspective view of a sample holder including sampleholder identifiers in accordance with example implementations of thepresent disclosure.

FIG. 28A is an isometric view of an automated sampling or dispensingdevice having sample vessels positioned in slots, numbers one to four,distal to a z-axis support.

FIG. 28B is a diagrammatic top view showing the automated sampling ordispensing device detecting sample vessels positioned in slots, numbersone to four, distal to a center slot through which a z-axis support canpass.

FIG. 29A is an isometric view of an automated sampling or dispensingdevice with sample vessels positioned in slots, numbers one to four,adjacent to a z-axis support.

FIG. 29B is a diagrammatic top view showing the automated sampling ordispensing device detecting sample vessels positioned in slots, numbersone to four, adjacent to a center slot through which a z-axis supportcan pass.

FIG. 30A is an isometric view of an automated sampling or dispensingdevice having a plurality of scientific standard solution vesselspositioned in slots accessible by a probe of the automated sampling ordispensing device in accordance with an example implementation of thepresent disclosure.

FIG. 30B is a diagrammatic bottom view of a scientific standard solutionvessel having a standard identifier associated therewith in accordancewith an example implementation of the present disclosure.

FIG. 30C is a diagrammatic top view showing the automated sampling ordispensing device detecting scientific standard solution vesselspositioned in slots, numbers one to three, in accordance with an exampleimplementation of the present disclosure.

FIG. 30D is a table showing information associated with scientificstandard solutions, where a standard identifier associated with one ofthe scientific standard solutions corresponds to an expired scientificstandard solution.

FIG. 31 is an isometric view of an automated sampling or dispensingdevice including an enclosed sample holder and a heating element inaccordance with example implementations of the present disclosure.

FIG. 32 is an isometric view of an automated sampling or dispensingdevice including an enclosed sample holder and a sampling base inaccordance with example implementations of the present disclosure.

FIG. 33 is an isometric view of a sampling base of an enclosed sampleholder, where the sampling base includes one or more protrusions formating with a support surface.

FIG. 34 is an isometric view illustrating a support surface for use withan automated sampling or dispensing device, where the support surfaceincludes recesses for mating with a sampling base in accordance withexample implementations of the present disclosure

DETAILED DESCRIPTION Overview

Often in laboratory settings, large numbers of samples are analyzed.Autosamplers are frequently used to test the composition of thesesamples. Using an autosampler allows more samples to be prepared andtested. During the sample preparation process, multiple samples may beprepared and placed in individual sample vessels at one time or over aperiod of time, which can lead to errors associated with sampleidentification. For example, laboratory personnel can place samplesprepared for testing in sample vessels without labeling the vessels oridentifying the sample vessels in some manner. This lack of labeling oridentification may lead to errors (e.g., misplacement of samples,misidentification of samples, etc.) when arranging the samples fortesting via autosampler or when entering the sample information into acomputer system connected to an autosampler. For example, the samplerack itself could be placed in an orientation relative to theautosampler that would result in skewed data analysis even if the samplevessels were properly arranged within the sample rack.

Accordingly, a sample identification system for an automated samplingdevice is disclosed that includes a sample holder having one or morecorresponding sample holder identifiers positioned proximate to thesample holder. The system also includes an identifier capture deviceconfigured to detect the one or more sample holder identifierspositioned proximate to the sample holder and generate a data signal inresponse thereto, the data signal corresponding to at least anorientation of the sample holder.

Example Implementations

FIG. 1 illustrates automated sampling device 100 in accordance with anexample implementation of the present disclosure. Automated samplingdevice 100 includes table top 102 and sample arm assembly 104. Further,sample holders 106 holding multiple sample vessels 108 are present ontable top 102 in preparation for sample assaying. It should beunderstood that automated sampling device 100 may assay from one to manyhundreds of samples (e.g., greater than 1200 samples in the exampleimplementation illustrated) in a given time depending upon testrequirements. Verification of a sample identify of a sample to beanalyzed is described with reference to FIGS. 20 through 29B.

In the implementation illustrated, sample arm assembly 104 includes az-axis support 110 and a sample probe support arm 112 that supports asample probe 114. As illustrated, the z-axis is aligned with gravity ora vertical axis. In use, sample probe 114 is mounted to sample probesupport arm 112, which is moved through space in three dimensions, orabout an axis having y-motion that is a substantially rotary motion andalong an axis having x-motion which is at least substantially horizontallinear motion or translation, and along a z-axis that is at leastsubstantially vertical, for linear motion or translation. In animplementation, the length of a sample probe support arm (the length ofan arm extending from the y-rotary axis) is no more than one-half thelength of a linear translation of the center slot (i.e., is no more thanhalf of the length of x-axis linear motion). In an implementation, thelength of the sample probe support arm is approximately equal toone-half the length of a linear translation of the center slot. Suchconfiguration allows nearly one hundred percent of the footprint of thetable to be accessed by the sample probe. Footprint is defined as beingsubstantially equivalent to an area encompassed by the area of the tabletop. In an additional implementation, the y-rotary axis of an automatedsampling device allows for access to sample vessels on either side ofthe x-axis motion of linear travel (i.e., on either side of the centerslot).

In an implementation, the components of sample arm assembly 104 areformed of carbon composite materials. Further, all exposed surfaces ofthe sample arm assembly 104 are made from inert or fluoropolymer-coveredmaterials (i.e., Teflon®). It should be understood, however, that thesample arm assembly may be made with various materials, includingaluminum, steel, plastic, and so forth.

In addition, sample arm assembly 104 is designed to attach to varioussurface supports including a table top. Such assembly may be attached toeither side of the center slot. In an implementation, table top 102 maybe mounted onto legs with casters 118, rollers and so forth. Suchconfiguration increases the mobility of the automated sampling device,thereby facilitating preparation of samples at a location separate fromthe analytical instruments. Further, this configuration provides storageroom underneath the table top which may be absent with bench-topautomated sampling devices. The height of the table is adjustable tocompensate for the effects of gravity on liquid flow rates whenself-aspirating sampling devices are used. The ability to adjust tabletop height also allows the automated sampling device to accommodatevarious sized sample vessels.

FIGS. 2A and 2B are additional illustrations of automated sampling ordispensing devices in which the sample arm assembly is attached to thedrive assembly via a center slot or a raised slot, respectively. In FIG.2A, automated sampling device 100 is comprised of sample arm assembly104 extending through center slot 120 and table top 102 including aplurality of recesses 124 and the channel 126. The sample arm assembly104 is attached to the drive assembly (not shown) via center slot 120.In an implementation, the plurality of recesses is coupled with sensorsfor detecting the location of sample holders. The sample holder locationinformation may then be transferred to a controller of a drive assemblycontrolling the sample arm assembly providing the alignment system. Theprevious configuration allows the sample arm assembly to detect thelocation of sample vessels on the table top at a given time. Channel 126runs along the edge of table top 102 to collect possible samplespillage.

In addition to FIG. 2A, FIG. 2B demonstrates an automated sampling ordispensing device including a sample arm assembly 104 attached to thedrive assembly 128 via a raised slot 129. In one implementation, amagnet 131 is attached to the end of the sample probe support arm 112which allows detection of a three-dimensional position in space wherethe magnet 131 is embedded into the sample probe support arm 112 and isdetected by a sensing means such as a Hall Effect sensor.

Referring now to FIG. 3, an exploded view of the components comprisingthe automated sampling device 100 is provided. The automated samplingdevice 100 is comprised of a table top 102 with center slot 120, driveassembly 128, sample arm assembly 104, housing 130, and controller 132.Sample arm assembly 104 includes z-axis support 110 attached to driveassembly 128, sample probe support arm 112 attached to z-axis support110, and sample probe 114 attached to sample probe support arm 112.Sample arm assembly 104 is controlled by drive assembly 128 andcontroller 132. In an implementation, drive assembly 128 causes samplearm assembly 104 to move along center slot 120, in translation along anaxis coaxial to z-axis support 110, and radially about the z-axis forinserting sample probe 114 into a sample vessel. Further, sample armassembly 104 is no more than one-half the length of a linear translationof the length of center slot 120. As previously mentioned, suchconfiguration allows nearly one hundred percent of the footprint to beaccessed by sample probe 114. In addition, automated sampling device 100is capable of assaying hundreds of samples at a given time withoutoperator assistance, thereby allowing the operator to perform othertasks. Moreover, it is possible to configure the automated samplingdevice to assay samples overnight, allowing work productivity to beincreased.

To accommodate gross differences in sample vessel height, sample probesupport arm 112 may be moved up or down z-axis support 110 as desiredprior to sample assaying. Once the desired position is reached, sampleprobe support arm 112 is secured into a fixed position on z-axis support110 and sample vessels containing samples may be loaded onto the tabletop. This feature allows the automated sampling device to be used onvarious sizes of sample vessels while still not having mechanical movingparts above stationary samples. Additionally, housing 130 encloses driveassembly 128 to protect the assembly from debris, dust, contaminates,and so forth. Housing 130 may be made of various materials, e.g., blowmolded polyethylene, and so forth.

FIGS. 4A and 4B illustrate an automated sampling device 200 inaccordance with another example implementation of the presentdisclosure, where multiple sampling arm assemblies (i.e., sample armassembly 206, 208, and 210) are mounted to the table top of theautomated sampling device. Automated sampling device 200 includesmultiple automated sampling devices attached to a table top at one time.A rail 202 is attached to the edge of table top 204 to enable theattachment of additional sample arm assemblies (i.e., sample armassembly 206 and 212). Utilization of additional sample arm assembliesallows multiple sample zones to be configured (i.e., a prep zone, anassaying zone, and so forth).

In additional implementations, various types of multiple rinse or eluentstations may be included in the automated sampling device. For instance,multiple rinse stations (i.e., 214 and 216) of the overflow typedesigned to reduce the chance of carry-over contamination may bepresent. Further, overflow rinse stations may contain a series ofdifferent chemical rinses to reduce contamination between sampleanalyses (e.g., surfactant, nitric acid, hydrofluoric acid, and/ordeionized water). For multiple eluent stations, the automated samplingdevice may contain such stations for step elution from a chromatographiccolumn.

Referring now to FIG. 5, an automated sampling device in accordance withanother example implementation of the present disclosure is described,where a table top having more than one plane is provided. Automatedsampling device 300 includes table top 302 which has more than oneplane, plane one 304 and plane two 306. Such configuration allows tabletop 302 to accommodate various sizes of vessels. For instance, theheight of vessels in plane two 306 may be taller than vessels in planeone 304 of table top 302.

FIGS. 6 and 7 further illustrate a drive assembly of automated samplingdevice 100 attached to a table top bottom. FIG. 6 provides an overviewof a drive assembly in accordance with the present disclosure, depictinga linear drive 134 running parallel to center slot 120 and connected tosled 128. FIG. 7 is an enlarged view of the drive assembly illustratedin FIG. 6. Drive assembly 100 is comprised of motor one 138, motor two140, motor three 142, sled 136, linear drive 134, and controller 132.Motor one 138 controls translation of a sample arm assembly's movementsalong the center slot 120 and is attached to table top bottom 144 andlinear drive 134. Various stepper motors may be used to controltranslation of the sample arm assembly's movements along center slot120. Moreover, it will be appreciated that various linear drives may beused including a worm drive. Motor two 140 controls angular rotation ofa sample arm assembly and is connected to sled 136. In animplementation, motor two 140 is a radial motor. Motor three 142controls vertical movement of a sample arm assembly and is attached tosled 136. Various stepper motors may be used for controlling verticalmovement of the sample arm assembly. In an additional implementation,motor three 142 comprises a slip-clutch system. Further, in accordancewith the present disclosure, the drive assembly may be hard-wired or, inanother implementation, controlled via wireless communication. Thus,wireless communications may be used to connect controller 132 with thedesired analytical instrument (not shown). Utilization of wirelesscommunications allows sample assaying to occur without requiringphysical connection with a controller computer increasing mobility ofthe automated sampling device.

FIG. 8 provides a detailed depiction of a sample arm assembly of anautomated sampling device in accordance with the first exampleimplementation of the present disclosure. As previously described, thesample arm assembly includes z-axis support 110 attached to a driveassembly (see FIGS. 6 and 7), sample probe support arm 112 attached toz-axis support 110, and sample probe 114 attached to sample probesupport arm 112. In an implementation, the sample arm assembly isattached to the drive assembly via the z-axis support extending througha center slot in the table top; in such implementation, the driveassembly is attached to a table top bottom. However, it should beunderstood that the drive assembly may be disposed in a variety oflocations including on top of the table top without departing from thescope of the present disclosure.

In an additional implementation in accordance with the presentdisclosure, sample tubing 146 is present to allow sample removal orreagent delivery as desired. Further, a slip bearing is built intosample probe 114 to prevent winding of sample tubing 146. It iscontemplated that the sample may be delivered to various types ofscientific instrumentation (e.g., an inductively couple plasma system, amass spectrometer, and so forth) or a number of other types of vessels(e.g., a waste collecting bucket following a wash step). It is furthercontemplated that the sample tubing may be flexible (as shown) or rigid,e.g., comprised of plastic, metal, and so forth. In anotherimplementation, the automated sampling device may be equipped with oneor more independent components for the purpose of sample preparation,sample dilution, addition of standards to samples or sampleacidification.

Referring to FIGS. 9A and 9B, tables for use with an automated samplingdevice are described in accordance with example implementations of thepresent disclosure. First, the table 102 includes a slot of length Lproviding for translation of the sample arm assembly along the length ofthe table. Further, the table 102 has a footprint for maximizing theusable area of the table 102. As illustrated in FIG. 9A, the table 102has a width L substantially equal to the length of the slot L. Moreover,the table 102 is twice as long as the slot, having a length of 2L.Further, the arm length of a sample probe assembly (as shown in FIGS. 1,2, and 3) is half the length of the slot, having length L/2. Thisconfiguration allows for approximately one hundred percent of thefootprint of the table to be accessed. In contrast, FIG. 9B illustratesan additional implementation in accordance with the present disclosurewhereby the table is the shape of a semi-circle and a non-centered slotsystem is employed.

Referring to FIG. 10, automated sampling or dispensing device 500includes a shroud 502. In an example implementation, the shroud 502substantially encloses the drive assembly 128 (FIG. 3) for protectingthe drive assembly from dust and debris, and/or preventing dust anddebris from the drive assembly from contaminating samples duringassaying.

FIG. 11 illustrates automated sampling device 600 completely enclosedwithin a hood 602. Use of the hood allows the operations inside the hoodto be isolated from the outside environment. The area within the hoodmay be ventilated to prevent the entry of contaminates such as bacteriaor air-borne substances. In one specific implementation, the air drawninto the enclosure is passed through a high efficiency particulate air(HEPA) filter. Further, processing of samples which contain hazardouschemicals within a hood allows such samples to be processed withoutfurther exposing the user to such chemicals during processing.

Referring generally to FIGS. 12 through 19, various implementations ofan enclosure for an automated sampling/dispensing device are provided.In general, the enclosure includes at least one support member. Thesupport member is generally perpendicular to a support surface on whichthe automated sampling/dispensing device is mounted. Further, a lid ismechanically coupled to the at least one support member for covering thesupport surface on which the automated sampling/dispensing device ismounted. Additionally, at least one flexible sheet is operationallycoupled to at least one of the lid or the at least one support member.The at least one support member may provide support to both the lid aswell as the at least one flexible sheet. The at least one supportmember, lid, and at least one flexible sheet enclose the automatedsampling device while allowing access to the device by retracting the atleast one flexible sheet.

The presently described example enclosures may minimize user exposure tothe enclosed samples by allowing the containment of potentiallyhazardous chemicals within such enclosure. Further, the use of at leastone flexible panel allows the enclosure to be shipped efficiently, asthe enclosure may be disassembled into smaller pieces and thus beshipped in a smaller box when compared to enclosures with non-flexiblepanels/doors. Moreover, the use of the at least one flexible panelallows the enclosure to be shaped to accommodate varying shapedautomated sampling and or dispensing devices and assemblies.

Referring to FIG. 12, an enclosure 700 for an automatedsampling/dispensing device is provided in which the enclosure 700surrounds an automated sampling/dispensing device mounted to a circularsupport surface 702. In an example implementation, the enclosure 700includes a lid 704 for covering the support surface 702 on which theautomated sampling/dispensing device is mounted. In such implementation,the lid 704 is generally equivalent in shape and size to that of thesupport surface 702 allowing the entire support surface 702 to beenclosed and available for use by a user. Further, an aperture forallowing the automated sampling/dispensing device to be connected withdevices external to the enclosure may be defined within the lid. Asillustrated in FIG. 12, an aperture defined within the lid 704 of theenclosure 700 allows a supply tube to the automated sampling/dispensingdevice to be connected with external laboratory analysis equipment. Inanother implementation, the enclosure 700 is designed to be airtight,allowing the enclosure 700 to contain potentially hazardous chemicalswithout requiring unnecessary exposure to laboratory personnel duringsample preparation or analysis.

As illustrated in FIG. 12, the enclosure 700 includes a first supportmember 706 and a second support member 708. The first and second supportmembers 706 and 708 are generally perpendicular to a support surface 702on which the automated sampling/dispensing device is mounted. Forexample, as illustrated in FIG. 12, the first support member 706 and thesecond support member 708 are centered generally one hundred and eightydegrees (180°) opposite from one another. Moreover, such support membersmay be mechanically coupled to the lid 704 of the enclosure 700 as wellas to the support surface 702. For instance, fasteners such as screws,bolts, nuts, and so forth may be used to fasten the support members tothe lid and support surface. In an implementation, all fasteners areeither metal-free or coated with an inert plastic coating to preventinteraction of such fasteners with chemical reagents or other substancesbeing used with the automated sampling/dispensing device. In anadditional implementation, an aperture may be formed within one or bothof the support members to allow tubes, cords, and so forth to beconnected to the automated sampling dispensing device contained withinthe enclosure as well as to external devices (e.g., laboratory analysisequipment), power sources, and so forth. It is contemplated that the lid704 as well as the first support member 706 and the second supportmember 708 may be formed of inert, light-weight material includingPlexiglas® (generically known as Lucite or polymethyl methacrylate.)

In additional implementations, as illustrated in FIG. 12, a firstflexible sheet 710 and a second flexible sheet 712 are operationallycoupled to at least one of the lid 708 or the first support member 706or the second support member 708. In an implementation, the firstflexible sheet 710 includes a first end and a second end. The first endof the first flexible sheet 710 includes a finished edge while thesecond end of the first flexible sheet 710 is fixedly coupled to thesecond support member 708. For example, the first end of the flexiblesheet 710 is finished with a hardened-plastic cover which extendssubstantially along the length of the first end of the first flexiblesheet 710. In addition, at least one guide member is attached to thefirst end of the first flexible sheet 710 to allow position of the firstflexible sheet to be varied.

As illustrated in FIGS. 13 and 14, the first end of the first flexiblesheet 710 includes a first guide member 714 and a second guide member716 to allow a user to slide the first flexible sheet 710 along an edgeof the support surface 702. In an implementation, the first guide member714 and the second guide member 716 are press-fit latches allowing auser to secure the flexible sheet at multiple positions along the edgeor side of the support surface. For example, a user may release theflexible sheet by applying pressure to the press-fit latches. Asillustrated in FIG. 14, a flexible sheet may be moved from a firstposition to a second position by guiding the first guide member 714along the edge of the lid 704 while the second guide member is detachedfrom the support surface 710. It is contemplated that additionalmechanisms may be employed to guide and secure the flexible sheet atvarious positions, including fasteners such as clips, pressure-sensitivescrews, and so forth. It is further contemplated that a channel may beformed within the support surface to provide an area in which a guidemember may slide and be secured.

In the present implementation, the second flexible side 712 includes afirst end and a second end. The first end of the second flexible sheet712 includes a finished edge while the second end of the second flexiblesheet 712 is fixedly coupled to the second support member 708. Forexample, the first end of the second flexible sheet 712 is finished witha hardened-plastic (e.g., Plexiglas®) cover which extends substantiallyalong the length of the first end of the second flexible sheet 712. Inaddition, at least one guide member is attached to the first end of thesecond flexible sheet 712 to allow position of the first flexible sheetto be varied. For instance, the first end of the second flexible sheet712 may include a first guide member 714 and a second guide member 716to allow a user to slide the second flexible sheet 712 along an edge orside of the support surface 702. In an implementation, the first guidemember 714 and the second guide member 716 are press-fit latchesallowing a user to secure the flexible sheet at multiple positions alongthe edge or side of the support surface. It is contemplated thatadditional mechanisms may be employed to guide and secure the flexiblesheet at various positions, including fasteners such as clips,pressure-sensitive screws, and so forth.

Referring to FIG. 15, the first and second flexible sheets have beenremoved to allow access to the support surface 702. In animplementation, the first and second flexible sheets are detachable. Thedetachable features of such sheets allow a user to load or removesamples efficiently from the support surface 702 so that a user does nothave to reposition the sheets in order to gain access to a supportsurface area. It is contemplated that one or both sheets may be removeddepending upon the needs of the user.

Referring to FIGS. 16 and 17, an additional example enclosure forenclosing an automated sampling/dispensing device is provided in whichthe automated sampling/dispensing device is a bench-top automatedsampling dispensing device. As illustrated in FIGS. 16 and 17, anenclosure 800 for a bench-top automated sampling dispensing device isconfigured in a similar manner as the enclosure 700 for a table-topautomated sampling/dispensing device. The enclosure 800 includes a firstsupport member 802 and a second support member 804 for supporting a lid806. In an example implementation, the lid 806 covers a support surface808 secured to a base 810 of the bench-top automated sampling/dispensingdevice. In such implementation, the lid 806 is generally equivalent inshape and size to that of the support surface 808, allowing the entiresupport surface 808 to be enclosed and available for use by a user.Further, the first 802 and second 804 support members are generallyperpendicular to the support surface 808.

As illustrated in FIGS. 16 and 17, the first support member 802 and thesecond support member 804 are centered generally one hundred and eightydegrees (180°) opposite from one another. For example, the first supportmember 802 is positioned on the front side of the automatedsampling/dispensing device (the front side defined as the side includinga user power control panel) while the second support member 804 ispositioned generally opposite the first support member 802 (e.g., to therear side of the automated sampling/dispensing device). Moreover, suchsupport members may be mechanically coupled to the lid 806 of theenclosure 800 as well as to the support surface 808. For instance,fasteners such as screws, bolts, nuts, and so forth may be used tofasten the support members to the lid and support surface. In animplementation, all fasteners are either metal-free or coated with aninert plastic coating to prevent interaction of such fasteners withchemical reagents or other substances being used with the automatedsampling/dispensing device.

It is contemplated that the lid 806 as well as the first support member802 and the second support member 804 may be formed of inert,light-weight material including Plexiglas®. It is further contemplatedthat the enclosure 800 may include an aperture within the lid or atleast one of the support members allowing for the automatedsampling/dispensing device to be connected with devices external to theenclosure. For example, an aperture may be defined within the lid forallowing a supply tube to the automated sampling/dispensing device to beconnected with external laboratory analysis equipment. In anotherimplementation, the enclosure 800 is designed to be airtight allowingthe enclosure to contain potentially harmful chemicals without requiringunnecessary exposure to laboratory personal during sample preparation oranalysis.

In additional example implementations, as illustrated in FIG. 17, afirst flexible sheet 812 and a second flexible sheet 814 are coupled toat least one of the lid 806 or the first support member 802 or thesecond support member 804. In an implementation, each flexible sheetincludes a first and second end. The first end of each flexible sheetincludes a finished edge while the second end of each flexible sheet isfixedly coupled to the second support member 804. For example, the firstend of the flexible sheet 812 is finished with a hardened-plastic cover(e.g., Plexiglas®) which extends substantially along the length of thefirst end of the first flexible sheet 812.

In further example implementations, at least one guide member isattached to the first end of each flexible sheet to allow the positionof each flexible sheet to be varied. As illustrated in FIG. 17, thefirst end of each flexible sheet includes a first guide member 816 and asecond guide member 818 to allow a user to slide each sheet along anedge of the lid 806 or support surface 808. In an implementation, thefirst guide member 816 and the second guide member 818 are press-fitlatches allowing a user to secure the flexible sheet at multiplepositions along the edge or side of the lid or support surface. Forexample, a user may release the flexible sheet by applying pressure tothe press-fit latches. As illustrated in FIG. 17, a flexible sheet maybe moved from a first position to a second position by guiding the firstguide member 816 along the edge of the lid 806 while the second guidemember 818 is detached from the support surface 808. It is contemplatedthat additional mechanisms may be employed to guide and secure theflexible sheet at various positions, including fasteners such as clips,pressure-sensitive screws, and so forth. It is further contemplated thata channel may be formed within the support surface to provide an area inwhich a guide member may slide and be secured.

It is contemplated that the first and second flexible sheets may bedetachable. The detachable features of such sheets allow a user to loador remove samples efficiently from the support surface 808 so that auser does not have to reposition the sheets in order to gain access to asupport surface area. It is contemplated that one or both sheets may beremoved depending upon the needs of the user.

Referring to FIGS. 18 and 19, a further example enclosure 900 forenclosing an automated sampling/dispensing device is provided in whichthe enclosure 900 includes a single flexible sheet or panel 902. Asillustrated in FIGS. 18 and 19, the enclosure 900 includes a pluralityof support walls and a single flexible sheet 902 for enclosing theautomated sampling/dispensing device mounted on a support surface 904.For example, the enclosure 900 may include three support walls and thesingle flexible sheet 902. In such example, a first side support walland a second side support wall provide support to a rear support wall inwhich the rear support wall is secured to an edge of the first sidesupport wall and an edge of the second side support wall. The rearsupport wall is generally opposite to that of the front of the enclosure(e.g., where the front of the enclosure includes the flexible sheet andis used to gain access to the automated sampling/dispensing device). Thefirst and second side support walls are configured to allow the flexiblesheet to be rolled along an outer edge of the first side support walland an outer edge of the second side support wall. It is contemplatedthat an aperture may be defined within at least one of the plurality ofwalls for allowing the enclosed apparatus to be connected with externaldevices or power sources.

With continued reference to FIGS. 18 and 19, the single flexible sheet902 includes a first and second edge. The first end of the flexiblesheet 902 includes a finished edge while the second end of the flexiblesheet 902 is fixedly coupled to the rear support wall. For example, thefirst end of the flexible sheet 902 is finished with a hardened-plasticcover which extends substantially along the length of the first end ofthe flexible sheet 902. To gain access to the interior of the enclosure900, the single flexible sheet 902 may be retracted with a first end ofthe first edge of the single flexible sheet 902 being secured to theouter edge of the first side support wall and a second end of the firstedge being secured to the outer edge of the second side support wall. Itis contemplated that various mechanisms may be employed to secure thefirst edge of the flexible sheet 902 to the side support edges includingpress fit latches, clips, screws, and so forth. In addition, theenclosure 900 may be mounted to an automated sampling/dispensing devicefor laboratory analysis equipment in which the enclosure may bepositioned to enclose such device by securing the enclosure to a supportarea supporting the device. Moreover, the single flexible sheet may bedetachable allowing a user access to the entire support surface area aswell as to the over-head support surface area.

Although the presently described enclosure focuses upon the use of suchenclosure with an automated sampling/dispensing device, it iscontemplated that such enclosure may be employed with a variety oflaboratory equipment in accordance with the present disclosure. It isfurther contemplated that example enclosures may be ventilated toprevent the entry of contaminates such as bacteria or air-bornesubstances into the external environment. For instance, the air drawninto the enclosure can be passed through a HEPA filter.

Referring now to FIG. 20, a sample identification system 1000 for anautomated sampling or dispensing device is shown in accordance with anexample implementation of the pressure disclosure. The sampleidentification system 1000 is configured to verify a sample identitybefore, during, and/or after sampling and/or dispensing by the automatedsampling or dispensing device occurs. As illustrated, the sampleidentification system 1000 includes a sample identifier 1002 and anidentifier capture device 1004. The sample identifier 1002 is configuredto provide indicia of the sample, such as a sample positioned in aparticular location with respect to the autosampler table top (e.g.,table top 102). The sample identifier 1002 may be configured forplacement on the autosampler table top, on a sample holder (e.g., sampleholder 106), on a sample vessel (e.g., sample vessel 108), or anotherlocation for reading by the identifier capture device 1004. In animplementation, the sample identifier 1002 is located on a base orbottom of a sample vessel (e.g., sample vessel 108), such as on thebottom of a test tube, such that the identifier capture device 1004 canaccess the sample identifier 1002 for processing/imaging of the sampleidentifier 1002 from a position beneath the sample vessel. In animplementation, the sample identifier 1002 includes a barcode configuredfor recognition by an optical reader (e.g., a barcode reader), where thebarcode is configured to represent a particular sample according to oneor more identifiers, including but not limited to, a position within atest rack, a position with respect to a table top, a particularidentification number corresponding to a predetermined sampling order ofsample vessels, and so forth. The barcode can include a data matrixtwo-dimensional (2D) barcode, such as a 12×12 matrix, a 13×13 matrix, a14×14 matrix, or any other suitable matrix. While square matrices areprovided as example data matrix barcodes, it is contemplated thatrectangular matrices also may be utilized. The sample identifier 1002can include other identification indicia including, but not limited to:characters and/or patterns configured for recognition by an opticalcamera or sensor; raised surfaces for recognition by touch sensors,optical sensors, and the like; illumination sources configured togenerate a particular color (or wavelength), pattern of light, etc.;other identification indicia configured for recognition by theidentifier capture device 1004; and so forth.

In an example implementation, the sample identification system 1000includes an identifier arm assembly 1006 (which may be separate from orinclude the sample arm assembly 104) supported by a z-axis support(which may be separate from or include the z-axis support 110). In animplementation, the identifier arm assembly 1006 is configured to movevertically with respect to the z-axis support (shown as 110 in FIG. 20).As illustrated in FIG. 1, the z-axis is aligned with gravity or avertical axis. The identifier arm assembly 1006 may include theidentifier capture device 1004 mounted thereto, such that the identifiercapture device 1004 can move to capture/image the sample identifier 1002of various samples supported by the autosampler table top 102, a sampleholder (e.g., sample holder 106), or other support surface. In use,identifier arm assembly 1006 is configured to be moved through space inthree dimensions, or about an axis having y-motion that is asubstantially rotary motion and along an axis having x-motion which isan at least substantially horizontal linear motion or translation, andalong a z-axis that is an at least substantially vertical, linear motionor translation. As such, the identifier arm assembly 1006 may beconfigured for movement through an R-theta range of motion, an x-y rangeof motion, and the like, such as between a rest position and anoperating position configured to image sample vessels including sampleidentifiers 1002. In an implementation, the identifier arm assembly 1006is configured to move independently from the sample arm assembly 104.

In an implementation, as shown in FIG. 20, the autosampler includes araised surface 1008 configured to be supported by the autosampler tabletop 102. The raised surface 1008 can support sample holders and samplevessels for access by the sample probe 114. The raised surface 1008 maybe positioned with respect to the table top 102 such that the raisedsurface 1008 and the table top 102 define a gap 1010 into which theidentifier arm assembly 1006 and identifier capture device 1004 canenter for access to the underside of the sample vessels (e.g., samplevessels 108) and associated sample identifiers 1002. For instance, inimplementations, the raised surface 1008 defines gaps 1012 in thesurface over which the sample vessels 108 having sample identifiers 1002positioned on a bottom surface are situated. In this manner, the sampleidentifiers 1002 at the base or bottom of the sample vessels 108 areaccessible to the identifier capture device 1004 when positioned beneaththe raised surface 1008 in the gap 1010 (such as shown in FIG. 22). Theraised surface 1008 can also define a center slot 1014 to correspond toat least a portion of the center slot 120 of the table top 102 to permitmotion of the sample arm assembly 104 across the raised surface 1008 andthe corresponding portion of the table top 102 (such as shown in FIGS.21A through 21C).

In example implementations, the autosampler includes sample holders(e.g., sample racks 106) configured to permit the identifier capturedevice 1004 to read the sample identifier 1002. For example, a base ofthe sample holders 106 may be constructed from a substantially clear,light transmissive, or transparent material. In other embodiments, thesample holder 106 may be constructed with an open bottom. Use of a lighttransmissive or transparent material may protect the identifier capturedevice 1004 from inadvertent contact with sample fluids within thesample vessels 108. In an implementation, the sample holders are formedof, or are coupled with, a material configured to reduce or eliminateglare associated with light when utilizing the identifier capture device1004. Alternatively or additionally, the identifier capture device 1004can include a protective coating or covering to protect the identifiercapture device 1004 from inadvertent contact with the sample fluids.Such coating or covering of may be configured to reduce or eliminateglare associated with light when utilizing the identifier capture device1004. In an implementation (such as shown in FIG. 23A), the sampleholder 106 includes a substantially transparent bottom 1120, throughwhich the image capture device 1004 can recognize the sample identifier1002 on a base of a sample vessel 108 supported by the sample holder106. In an implementation (such as shown in FIGS. 22 and 23B), thesample holder 106 defines a first set of apertures 1016, through whichthe sample vessels 108 may pass, and a second set of apertures 1018which prohibit at least a portion of the sample vessels 108 fromcompletely passing through. For instance, the first set of apertures1016 can have a larger cross-sectional area (e.g., larger diameter withlarger circular cross-sectional area) than the second set of apertures1018, where the second set of apertures 1018 have a cross-sectional areathat is smaller than a cross-sectional area of the sample vessels 108(e.g., the diameter of the second set of apertures 1018 is less than thediameter of a portion of the sample vessels 1018). Such a configurationof apertures may provide an exposed bottom portion of the sample vessel108 such that the sample identifier 1002 is unobstructed with respect tothe identifier capture device 1004. In an example implementation, thesample holder 106 includes a raised base, such that the sample vessels108 within the holder 106 are positioned over the autosampler table top102 with a gap between the base of the sample holder 106 and theautosampler table top 102. Such a configuration may permit theidentifier capture device 1004 access beneath the sample holder to readthe sample identifier 1002. It is contemplated that the size, shape, andmaterials comprising the sample holder 106 may vary depending on thetype, size, and shape of the identifier capture device 1004 used in thesample identification system 1000, and the type of samples to beanalyzed (e.g., corrosive, inert, and so forth).

The autosampler may be configured to align the identifier capture device1004 with the sample probe 114. For example, as shown in FIG. 24, theidentifier capture device 1004 includes an alignment light source 1022configured to project light (e.g., a light beam) toward the sample probeto provide a visual indication of an alignment of the identifier capturedevice 1004 with the sample probe 114. In an implementation, the raisedsurface 1008 defines an aperture 1024 through which the alignment lightsource 1022 can project the light toward the sample probe 114. Where thepositioning of the sample probe 114 with respect to the identifiercapture device 1004 is not aligned, one or more of the sample armassembly 104 and the identifier arm assembly 1006 can be repositioneduntil the alignment is satisfactory. The repositioning can beaccomplished through an automatic, motorized movement of the sample armassembly 104 and the identifier arm assembly 1006 (e.g., through controlof drive assembly 100) or through manual means. For example, one or moreof the sample arm assembly 104 and the identifier arm assembly 1006 canbe secured with a set screw, with press fit, with a friction clamp, andso forth. The alignment may assist in accuracy of the correspondencebetween the imaged sample identifier 1002 by the identifier capturedevice 1004 and the actual sample drawn by the sample probe 114 from thesample vessel 108.

The identifier capture device 1004 is configured to capture, image, orotherwise recognize the sample identifier 1002. Accordingly, in animplementation such as shown in FIG. 25, the identifier capture device1004 includes an imaging device 1026, a light source 1028 (e.g., a flashsource), and the alignment light source 1022. The imaging device 1026can capture video images of the sample identifiers 1002 and surroundingareas, such that the imaging device 1026 can be associated with adisplay for displaying the captured images, such as on a live orcontinuous basis. In an implementation, the imaging device is configuredto provide still images of a target. The light source 1028 may beconfigured to illuminate the bottom of the sample vessels 108 such thatthe sample identifier 1002 has increased visibility to the imagingdevice 1026 in order to image the sample identifier 1002. In animplementation, the identifier capture device 1004 is aided by anexternal light source 1030 to provide illumination in addition to orinstead of the light source 1028. For example, the external light source1030 can be mounted on the identifier arm assembly 1006.

In implementations, the identifier capture device 1004 is angledrelative to the identifier arm assembly 1006, such that the imagingdevice 1026 views the sample identifier 1002 on the base of the samplevessel 108 at an angle from the horizontal or with respect to theorientation of the autosampler table top. For example, as shown in FIG.26A, the identifier capture device 1004 and the identifier arm assembly1006 are oriented at an angle of alpha (a) (e.g., 15 degrees) relativeto each other, where a top surface of the identifier arm assembly 1006is substantially perpendicular to the alignment axis (e.g.,substantially parallel to the surface of table top). In FIG. 26B, theidentifier capture device 1004 and the identifier arm assembly 1006 areoriented at an angle of alpha (a) (e.g., 15 degrees) relative to eachother, where a top surface of the identifier capture device 1004 issubstantially perpendicular to the alignment axis (e.g., substantiallyparallel to the surface of table top). Various configurations of theangle are contemplated, where the angle utilized may depend on theparticular imaging device 1026 utilized in the identifier capture device1004.

The sample identification system 1000 is configured to verify dataassociated with the sample identifier 1002, and correspondingly, thesample uniquely associated with the sample identifier 1002, before,during, or after sampling of the sample by the autosampler samplingprobe (e.g., sample probe 114). The sample identification system 1000may collect and process data associated with the sample identifier 1002,where the data can include, but is not limited to, the location of asample (e.g., a location on the autosampler table top 102, a locationwithin a sample rack 106, a particular sample vessel 108, and so forth),a timestamp of when a sample is taken (e.g., by the sample probe 114),presence or absence of a sample, type or extent of analysis to beperformed on a sample, dilution factor, and the like. In animplementation, the sample identifier 1002 is read by the identifiercapture device 1004 for conversion to a serial number, where dataassociated with the serial number is associated with the particularsample vessel that includes the sample identifier 1002. In this manner,the sample identifier 1002 can associate data including, but not limitedto, the location of a sample, timestamp of when a sample is taken,presence or absence of a sample, type or extent of analysis to beperformed on a sample, dilution factor, and the like with a particularsample in the vessel, where the data can be stored in a memory device ofa data system to be correlated with the serial number stored by thesample identifier 1002. In an implementation, the sample identificationsystem 1000 can be configured for dilution factor control of a sample.For example, the data associated with a particular sample identifier1002 can include a dilution factor for offline or online dilution of asample. In an implementation, the sample identification system 1000 isconfigured to populate data of prepared samples, such as by filling instandards data into data tables automatically, based on the sampleidentifier 1002 and the results of a sample analysis by an analyzer(e.g., mass spectrometer, gas chromatograph, liquid chromatograph, andthe like) of the particular sample.

The sample identifier 1002 can be associated with and/or compriseinformation including, but not necessarily limited to: a sample vialidentification number, a destination vial identification number, adilution factor (DF), a final volume, a sample volume, a diluent volume,a diluent location, and so forth. For example, a first barcode is placedon a sample vial and associated with a desired dilution factor and adesired final volume. A destination vial includes a second barcodeassociated with the first barcode. The system 1000 uses informationobtained from the first barcode to dilute a portion of a samplecontained in the sample vial. For instance, the system 1000 identifiesthe destination vial using the second barcode and deposits a portion ofthe sample into the destination vial. The system 1000 also deposits anamount of diluent sufficient to provide the DF and final volumespecified by the first barcode.

In another embodiment, the first barcode is representative of a samplevial identification number, and the sample identification number isassociated with a desired dilution factor and a desired final volume. Insome embodiments, a user interface (e.g., a graphical user interface)included with an information handling system device operatively coupledwith the sample identification system 1000 via a communicationsinterface is used to associate the first barcode with the desireddilution factor and the desired final volume. For instance, the desireddilution factor and the desired final volume can be stored in anelectronic database with the first barcode. A destination vial includesa second barcode associated with the first barcode (e.g., via theelectronic database). The system 1000 uses information associated withthe first barcode in the electronic database to dilute a portion of thesample contained in the sample vial. For instance, the system 1000identifies the destination vial using the association with the secondbarcode and deposits a portion of the sample into the destination vial.The system 1000 also deposits an amount of diluent sufficient to providethe DF and final volume specified in the electronic database.

However, these off-line embodiments are provided by way of example onlyand are not meant to limit the present disclosure. In other embodiments,dilution of a sample can be performed on-line. For example, the system1000 uses information obtained from a barcode to dilute a portion of asample contained in the sample vial by mixing the sample portion with anamount of diluent sufficient to provide a desired DF and a desired finalvolume as specified by a first barcode, associated with the firstbarcode in an electronic database, and so forth.

The data collected by the sample identification system 1000 may betransferred to another system for identity verification. In an exampleimplementation, the data collected by the sample identification system1000 is transferred to a laboratory information management system (LIMS)and/or a laboratory instrument to verify the identity of a measuredsample. The identifier capture device 1004 may be configured for wiredor wireless data transfer between the sample identification system 1000and the LIMS, laboratory instrument, or other device. In an exampleembodiment, the identifier capture device 1004 is configured for fiberoptic data transfer. The identifier capture device 1004 may beconfigured for control by the sample identification system 1000 viawired or wireless control mechanisms.

A sample identification system 1000, including some or all of itscomponents, can operate under computer control. For example, a processorcan be included with or in a sample identification system 1000 tocontrol the components and functions of systems 1000 described hereinusing software, firmware, hardware (e.g., fixed logic circuitry), manualprocessing, or a combination thereof. The terms “controller,”“functionality,” “service,” and “logic” as used herein generallyrepresent software, firmware, hardware, or a combination of software,firmware, or hardware in conjunction with controlling the systems 1000.In the case of a software implementation, the module, functionality, orlogic represents program code that performs specified tasks whenexecuted on a processor (e.g., central processing unit (CPU) or CPUs).The program code can be stored in one or more computer-readable memorydevices (e.g., internal memory and/or one or more tangible media), andso on. The structures, functions, approaches, and techniques describedherein can be implemented on a variety of commercial computing platformshaving a variety of processors.

A processor provides processing functionality for the system 1000 andcan include any number of processors, micro-controllers, or otherprocessing systems, and resident or external memory for storing data andother information accessed or generated by the system 1000. Theprocessor can execute one or more software programs that implementtechniques described herein. The processor is not limited by thematerials from which it is formed or the processing mechanisms employedtherein and, as such, can be implemented via semiconductor(s) and/ortransistors (e.g., using electronic integrated circuit (IC) components),and so forth.

The system 1000 also includes a memory. The memory is an example oftangible, computer-readable storage medium that provides storagefunctionality to store various data associated with operation of thesystem 1000, such as software programs and/or code segments, or otherdata to instruct the processor, and possibly other components of thesystem 1000, to perform the functionality described herein. Thus, thememory can store data, such as a program of instructions for operatingthe system 1000 (including its components), and so forth. It is notedthat while a single memory is described, a wide variety of types andcombinations of memory (e.g., tangible, non-transitory memory) can beemployed. The memory can be integral with the processor, can comprisestand-alone memory, or can be a combination of both. The memory caninclude, but is not necessarily limited to: removable and non-removablememory components, such as random-access memory (RAM), read-only memory(ROM), flash memory (e.g., a secure digital (SD) memory card, a mini-SDmemory card, and/or a micro-SD memory card), magnetic memory, opticalmemory, universal serial bus (USB) memory devices, hard disk memory,external memory, and so forth. In implementations, the system 1000and/or the memory can include removable integrated circuit card (ICC)memory, such as memory provided by a subscriber identity module (SIM)card, a universal subscriber identity module (USIM) card, a universalintegrated circuit card (UICC), and so on.

The system 1000 includes a communications interface. The communicationsinterface is operatively configured to communicate with components ofthe system 1000. For example, the communications interface can beconfigured to transmit data for storage in the system 1000, retrievedata from storage in the system 1000, and so forth. The communicationsinterface is also communicatively coupled with the processor tofacilitate data transfer between components of the system 1000 and theprocessor (e.g., for communicating inputs to the processor received froma device communicatively coupled with the system 1000 and/orcommunicating output to a device communicatively coupled with the system1000. It is noted that while the communications interface is describedas a component of a system 1000, one or more components of thecommunications interface can be implemented as external componentscommunicatively coupled to the system 1000 via a wired and/or wirelessconnection. The system 1000 can also comprise and/or connect to one ormore input/output (I/O) devices (e.g., via the communications interface)including, but not necessarily limited to: a display, a mouse, and soon.

The communications interface and/or the processor can be configured tocommunicate with a variety of different networks including, but notnecessarily limited to: a wide-area cellular telephone network, such asa 3G cellular network, a 4G cellular network, or a global system formobile communications (GSM) network; a wireless computer communicationsnetwork, such as a WiFi network (e.g., a wireless local area network(WLAN) operated using IEEE 802.11 network standards); an internet; theInternet; a wide area network (WAN); a local area network (LAN); apersonal area network (PAN) (e.g., a wireless personal area network(WPAN) operated using IEEE 802.15 network standards); a public telephonenetwork; an extranet; an intranet; and so on. However, this list isprovided by way of example only and is not meant to limit the presentdisclosure. Further, the communications interface can be configured tocommunicate with a single network or multiple networks across differentaccess points.

In an implementation, as shown in FIG. 27, the sample holder 106includes a sample holder identifier 402 positioned on a bottom portion404 of the sample holder 106. The bottom portion 404 can correspond to aside of the sample holder 106 that is opposite or distal a side of thesample holder 106 that receives the sample vessels 108 via the first setof apertures 1016 (e.g., for holding the sample vessels upright foraccess by the sample probe 114). For example, the bottom portion 104 candefine the second set of apertures 1018, the bottom portion can includethe transparent bottom 1120, or so forth. The sample holder identifier402 is identifiable by an identifier capture device, such as theidentifier capture device 1004 of the sample identification system 1000.The sample holder identifier 402 provides a unique identification of thesample holder 106, where such unique identification can correspond toidentification information including, but not limited to, sampleidentities, analysis methods associated with samples held in samplevessels 108 in the sample holder 106, elements/species associated withsamples held in sample vessels 108 in the sample holder 106, dilutionfactors associated with samples held in sample vessels 108 in the sampleholder 106, weights associated with samples held in sample vessels 108in the sample holder 106, final volumes associated with samples held insample vessels 108 in the sample holder 106, and the like. Suchcorresponding identification information can be stored in a memorydevice accessible by one or more components of the automated samplingdevice or associated scientific instrumentation coupled thereto. Forexample, the sample holder identifier 402 may include one or more of abarcode or a QR code associated with the unique identification of thesample holder 106. In an implementation, the sample holder identifier402 includes a data matrix two-dimensional barcode in a square matrixform (e.g., a 12×12 matrix, a 13×13 matrix, a 14×14 matrix, a 144×144matrix etc.). While square matrices are provided as example data matrixbarcodes, it is contemplated that rectangular matrices (e.g., a 8×18matrix, a 16×48 matrix, etc.), or any other suitable matrix also may beutilized. The sample holder identifier 402 can include otheridentification indicia including, but not limited to: characters and/orpatterns configured for recognition by an optical camera or sensor;raised surfaces for recognition by touch sensors, optical sensors, andthe like; illumination sources configured to generate a particular color(or wavelength), pattern of light, etc.; other identification indiciaconfigured for recognition by the identifier capture device 1004; and soforth.

While the sample holder identifier 402 is shown in FIG. 27 on the bottomportion 404 of the sample holder 106, other configurations of the sampleholder identifier 402 with respect to the sample holder 106 can beutilized, including, but not limited to, the sample holder identifier402 being located on a top portion, a side portion, a support postportion, or the like, such that an identifier capture device canrecognize the sample holder identifier 402. For example, in animplementation, the sample holder identifier 402 is positioned on a topportion of the sample holder 106 (e.g., proximate the first set ofapertures 1016), for access by an identifier capture device associatedwith the sample arm assembly 104, the z-axis support 110, the sampleprobe 114, or other perspective above the table top 102.

In an implementation, the sample holder identifier 402 includes morethan one sample holder identifier (e.g., FIG. 27 shows two sample holderidentifiers, labeled 402 a and 402 b), where each sample holderidentifier corresponds to a different orientation of the sample holder106. For example, sample holder identifier 402 a can includeidentification information that corresponds to a top, front, or sideorientation of the sample holder 106, whereas sample holder identifier402 b can include identification information that corresponds to abottom, back, or different side orientation of the sample holder 106. Asused herein, the orientation of the sample holder 106 can refer to aplacement orientation used to align the sample holder 106 on a surfaceof an autosampler or sample identification device for processing ofsamples (e.g., on raised surface 1008, on table top 102, etc.). Forexample, the placement orientation can identify an orientation and/orposition of the sample holder 106 relative to the center slot 1014, thesample arm assembly 104, the z-axis support 110, the sample probe 114,or other component or portion of the automated sampling device 100.

In an implementation, as depicted in FIGS. 28A and 28B, sample vessels108 are positioned in slots 406 (or apertures), numbers one to four,distal to a z-axis support 110 of an automated sampling or dispensingdevice, where the slots correspond to positions in the sample holder 106configured to hold sample vessels 108. The sample holder 106 can includelabels to identify the particular slots 406 to a user, such as toprovide an order in which to place the sample vessels within the slots406. For example, the sample holder 106 can include labels to identifythe slots 406 with the numbers corresponding to those diagrammaticallyshown in FIG. 28B. In an implementation, the sample holder identifier402 b is positioned on the same side of the sample holder 106 as theslot 406 labeled with position one, such that when the sample holder 106is placed in the reverse or flipped orientation, each of the sampleholder identifier 402 b and the side of the sample holder 106 having theslot 406 labeled with position one will be adjacent the center slot 120(e.g., as shown in FIG. 29A). For example, the sample holder identifier402 a can be positioned on the opposite side of the sample holder 106(e.g., on the bottom portion of the sample holder 106) as the slot 406labeled with position one (e.g., the first designation in a series, suchas the numbering series of slots 406), such that when the sample holder106 is placed in the standard orientation, the sample holder identifier402 a will be adjacent the center slot 120, and the side of the sampleholder 106 having the slot 406 labeled with position one will be distalthe center slot 120 (e.g., as shown in FIG. 28A). The sample holder 106can include a sample holder identifier 402 configured to provide dynamicdata associated with the sample holder 106 including, but not limitedto, a unique rack identification (ID), a position of the sample holder106, an orientation of the sample holder 106 (e.g., a standardorientation, a reverse or flipped orientation, etc.), an alignment ofthe sample holder 106, and the like. For example, the sample holderidentifier 402 can correspond to the dynamic data stored in memory,whereby a data controller, system processor, or the like can assignand/or update the dynamic data, such as responsive to user input,responsive to automatic implementation by the system 100, or the like.In an implementation, the system 1000 determines an orientation a sampleholder 106 (e.g., standard orientation shown in FIGS. 28A, 28B; reverseor flipped orientation shown in FIGS. 29A, 29B) by positioning theidentifier capture device 1004 in a sample holder read position (shownas 408 in FIGS. 27 and 28A) that corresponds to a position underneaththe sample holder identifier 402 when the sample holder 106 is placed onthe table top 102, the raised surface 1008, or otherwise positioned forallowing access to the sample vessels 108 by the sample probe 114.Generally, the sample holder reader position corresponds to thepositioning of the identifier capture device 1004 to read the sampleholder identifier 402. The system 1000 can include a plurality of sampleholder read positions when multiple sample holders 106 are present onthe on the table top 102, the raised surface 1008, etc. In animplementation, a user can input information associated with theplacement of the sample holders 106, including location and number ofthe individual sample holders 106, whereby the system 1000 canautomatically scan only the relevant sample holder read positions toidentify the orientation of the sample holders 106 present (e.g., byignoring sample holder read positions at locations where no sampleholder 106 is present).

The sample holder identifier 402 can then inform the system 1000 aboutwhether the sample holder 106 is in a standard orientation or a reverseor flipped orientation. The system 1000 can manipulate the operationalpositioning of the sample probe 114 based on the detected orientation ofthe sample holder 106. For example, when the sample holder 106 isdetermined to be in the standard orientation (e.g., the identifiercapture device 1004 detects the sample holder identifier 402A in thesample holder read position), the system 1000 can operate according to astandard orientation protocol. The standard orientation protocol caninvolve, for example, initially positioning the sample probe 114 tomeasure the sample vessel 108 in position one of slots 406, shown inFIG. 28B, where position one is distal to the center slot 120, andproceeding to position the sample probe 114 to sequentially measure theremaining sample vessels 108 based on slot number (e.g., continuing toslots two, three, and four). When the sample holder 106 is determined tobe in the reverse or flipped orientation (e.g., the identifier capturedevice 1004 detects the sample holder identifier 402B in the sampleholder read position), the system 1000 can operate according to areverse orientation protocol. The reverse orientation protocol caninvolve, for example, initially positioning the sample probe 114 tomeasure the sample vessel 108 in position one of slots 406, shown inFIG. 29B, where position one is adjacent to the center slot 120, andproceeding to position the sample probe 114 to sequentially measure theremaining sample vessels 108 based on slot number (e.g., continuing toslots two, three, and four). In implementations, the system 1000 canprovide an alert (e.g., via a display device) based upon detection ofthe particular orientation of the sample holder 106. For example, when areverse orientation of the sample holder 106 is detected, the system1000 can display an alert to an operation, notifying that the sampleholder 106 is in the reverse orientation. The system 1000 can receiveuser input to continue operation with the sample holder 106 in thereverse orientation (e.g., by implementing the reverse orientationprotocol), or alternatively, can receive user input to delay operation,such as to permit repositioning of the sample holder 106 and/or samplevessels 108. When user input is received to delay operation, the system1000 may scan any sample holder identifiers 402 at the sample holderread position and/or may scan the sample identifiers 1002 of any samplevessels 108 present in the sample holder upon resuming operation, suchas to determine whether the user placed the sample holder 106 in thestandard orientation, in the reverse orientation, changed the order ofsample vessels 108 within the sample holder 106, change the number ofsample vessels 108 within the sample holder 106, or the like.

In implementations, the sample vessel positions shown in FIG. 28Acorrespond with a graphical representation of the sample vesselspositions within the sample holder 106 shown on a communicationsinterface operably coupled to the automated sampling or dispensingdevice 100, as shown in FIG. 28B. The communications interface can alsoshow the presence (shown as 410) or absence (shown as 412) of the samplevessel 108 within a particular sample slot 406, whereby detection of thesample vessel 108 within a particular slot 406 is automatically shown asthe presence 410 of the sample vessels 108 via the communicationsinterface. For example, the automated sampling or dispensing device(e.g., via identifier capture device 1004) can detect sample vessels 108positioned in the slots 406 via the sample identifiers 1002, where thecommunications interface can provide a graphical representation (e.g.,as shown in FIG. 28B) of the presence of the sample vessels 108 relativeto the orientation of the sample holder 106 (e.g., via detection of thesample holder identifier 402 information), such that the sample vessels108 are shown distal the center slot 120 in the properorder/configuration. The presence of the particular sample vessels 108in the slots 406 and the orientation of the sample holder 106 providethe system 1000 with the information as to which slots 406 the sampleprobe 114 should position above during its operation protocol. Thecommunications interface can generate a sample list based on sampleidentifiers 1002 associated with the sample vessels 108 positioned inthe sample holder 106 and based on the sample holder identifier 402positioned on the sample holder 106. Such sample list can be generatedafter scanning the sample identifiers 1002 and the sample holderidentifier 402, and can be populated with data associated with theanalysis of the samples once completed, or on an individual samplevessel basis.

In an implementation, as depicted in FIG. 29A, an automated sampling ordispensing device is shown with sample vessels 108 positioned in slots406, numbers one to four, adjacent to a z-axis support 110. Forinstance, the sample rack is in the reverse or flipped orientation,where the samples vessels 108 are positioned in a reverse or flippedorientation as compared to the positioning in FIGS. 28A and 28B. Byincluding one or more sample holder identifier 402, the automatedsampling or dispensing device can detect the reverse or flippedorientation of the samples and maintain an accurate accounting for thesamples and the analyses of the samples. For example, the communicationsinterface can provide a graphical representation (e.g., as shown in FIG.29B) of the presence of the sample vessels 108 in the slots, relative tothe sample holder identifier 402 information, such that the samplevessels 108 are shown adjacent the center slot 120 in the properorder/configuration.

While sample holder identifiers 402 and sample identifiers 1002 havebeen described herein, it is noted that other aspects or components ofthe automated sampling or dispensing device can include labelsconfigured for detection by identifier capture device 1004. For example,diluents, diluent holders, standards, standard holders, eluents, eluentholders, buffers, buffer holders, waste vessels, and the like caninclude identifiers (e.g., data matrix two-dimensional barcode) fortracking of the positioning of the respective items.

In an implementation, as shown in FIG. 30A, a plurality of scientificstandard solution vessels 1032 are positioned relative to an automatedsampling or dispensing device (e.g., sample identification system 1000),where the scientific standard solution vessels 1032 and any scientificstandard solutions contained therein are accessible by a sample probe(e.g., sample probe 114). The scientific standard solution vessels 1032each include one or more standard identifiers 1034 positioned on thescientific standard solution vessels 1032. For example, the standardidentifiers can be positioned on a portion (e.g., bottom portion, topportion, side portion, etc.) of the scientific standard solution vessels1032 for access by the identifier capture device 1004. FIG. 30B showsthe standard identifier 1034 positioned on a bottom portion of ascientific standard solution vessel 1032. The standard identifier 1034can include, but is not limited to, one or more of a barcode or a QRcode. In an implementation, the standard identifier 1034 includes a datamatrix two-dimensional barcode in a square matrix form (e.g., a 12×12matrix, a 13×13 matrix, a 14×14 matrix, a 144×144 matrix etc.). Whilesquare matrices are provided as example data matrix barcodes, it iscontemplated that rectangular matrices (e.g., a 8×18 matrix, a 16×48matrix, etc.), or any other suitable matrix also may be utilized. Thestandard identifier 1034 can include other identification indiciaincluding, but not limited to: characters and/or patterns configured forrecognition by an optical camera or sensor; raised surfaces forrecognition by touch sensors, optical sensors, and the like;illumination sources configured to generate a particular color (orwavelength), pattern of light, etc.; other identification indiciaconfigured for recognition by the identifier capture device 1004; and soforth. The standard identifier 1034 is identifiable by an identifiercapture device, such as the identifier capture device 1004 of the sampleidentification system 1000. The standard identifier 1034 can provide aunique identification of the scientific standard solution vessel 1032and/or the scientific standard solution contained therein, where suchunique identification can correspond to identification informationincluding, but not limited to, standard identity, expiration statusassociated with the standard, analysis methods associated with thestandard, matrices associated with the standard, elements/speciesassociated with the standard, concentrations of the standard, and thelike. Such corresponding identification information can be stored in amemory device accessible by one or more components of the automatedsampling device or associated scientific instrumentation coupledthereto. In an implementation, the standard identifier 1034 isassociated with an expiration status associated with a scientificstandard solution located in the scientific standard solution vessel1032 on which the standard identifier 1034 is positioned. The expirationstatus can include, but is not limited to, an expiration date, anindication that the scientific standard solution is expired, anindication that the scientific standard solution is about to expire (thecurrent date is within a threshold time period (e.g., one day, one week,one month, etc.) of the expiration date), an initial preparation date,and so forth.

In an implementation, when the standard identifier 1034 is scannedand/or observed by the identifier capture device 1004, the identifiercapture device 1004 can generate one or more data signals associatedwith the standard identifier 1034 that is associated with the expirationstatus of the scientific standard solution contained in the particularscientific standard solution vessel 1032. For example, the system 1000can initiate a standard identifier protocol whereby the identifiercapture device 1004 passes underneath the scientific standard solutionvessels 1032 in a sequential manner (e.g., beginning at position 1 shownin FIG. 30C, continuing on to position 2, then continuing onto position3, then continuing onto position 4, then, continuing onto position 5,etc.) to detect the presence (shown as 1036 in FIG. 30C) or absence(shown as 1038 in FIG. 30C) of a scientific standard solution vessel1032 in a particular standard position. For instance, when theidentifier capture device 1004 recognizes the standard identifiers 1034associated with the scientific standard solution vessels 1032, thelocation of the scientific standard solution vessels 1032 can be shownvia a communications interface, as depicted in FIG. 30C. Further, dataassociated with the scientific standard solutions contained in thescientific standard solution vessels 1032, provided by the standardidentifiers 1034, can be displayed via the communications interface,such as shown in FIG. 30D (e.g., in tabular form). The communicationsinterface can provide an expiration status of the individual scientificstandard solutions, which can be displayed relative to the positions ofthe scientific standard solution vessels 1032. For example, FIG. 30Dincludes an expiration date or an expiration status 1040 of each of thethree scientific standard solutions identified by the identifier capturedevice 1004, where the communications interface provides an indicationthat the scientific standard solution associated with position or vial 3has expired (e.g., such as by comparing an expiry date with a currentdate). In an implementation, the system 1000 can provide an alert (e.g.,via a display device) based upon detection of an expired scientificstandard solution present in a scientific standard solution vessels 1032via the standard identifier 1034 (e.g., the expiration status isindicative of an expired scientific standard solution). The system 1000can automatically stop operation of the sample probe 114 upon detectionof the expired scientific standard solution to prevent addition of theexpired scientific standard solution to any of the sample vessels 108.The system 1000 can receive user input to delay operation, such as topermit placement of a new scientific standard solution vessel 1032 inthe position occupied by the expired scientific standard solution. Whenuser input is received to delay operation, the system 1000 may scan thestandard identifiers 1034 of any scientific standard solution vessels1032 present upon resuming operation, such as to determine whether theuser changed the order of scientific standard solution vessels 1032,change the number of scientific standard solution vessels 1032,introduced new scientific standard solution vessel(s) 1032 having newstandard identifier(s) 1034, or the like.

In an implementation, as depicted in FIGS. 31 through 34, theautosampler/dispensing device includes an enclosed sample holder 1102.For example, the enclosed sample holder 1102 can have solid sideportions, forming a block. The enclosed sample holder 1102 may beconstructed from a heat resistive and/or heat retentive materialincluding, but not necessarily limited to: aluminum, tungsten, nickel,titanium, graphite, heat resistant plastic, and so forth. The enclosedsample holder 1102 can be configured to heat the samples by dispersingheat throughout the sample vessels 108. For example, the enclosed sampleholder 1102 can be removably coupled to a heating element 1104 (such asshown in FIG. 31). In some implementations, the heating element 1104comprises a relatively flat platform configured to receive the enclosedsample holder 1102 (e.g. a bottom portion of the enclosed sample holder1102 rests on the platform). However other types of heating elements maybe utilized. Heating the samples vessels 108 can reduce the viscosity ofthe samples (e.g., to improve the accuracy of the automated sampling ordispensing device, to facilitate transfer of a viscous sample through ananalytical instrument and/or sample preparation system, or so forth).Alternatively, the enclosed sample holder 1102 can be utilized to reduceexposure of high sensitivity samples (e.g., light-sensitive samples). Insome implementations, the enclosed sample holder 1102 defines a firstset of apertures 1016, through which the sample vessels 108 may pass,and a second set of apertures 1018 which prohibit at least a portion ofthe sample vessels 108 from completely passing through, as describedabove. In an implementation (such as shown in FIGS. 31 through 33), theenclosed sample holder 1102 includes a sampling base 1106. The samplingbase 1106 can be removably coupled to the enclosed sample holder 1102 sothat the bottom portion of the enclosed sample holder 1102 sits withinthe sampling base 1106. For example, the sampling base can include oneor more rim portions 1108 configured to retain the enclosed sampleholder 1102. In some implementations, the sampling base 1106 can includea third set of apertures 1110 that correspond to the second set ofapertures 1018 (e.g., the diameter of the third set of apertures 1110 isapproximately equal to the diameter of the second set of apertures1018). Such a configuration of apertures may provide an exposed bottomportion of the sample vessel 108 such that a sample identifier 1002positioned on the base of the sample vessel 108 is unobstructed withrespect to an identifier capture device 1004. Alternatively, a bottomportion of the enclosed sample holder 1102 and/or the sampling base 1106may be constructed from a substantially clear, light transmissive, ortransparent material to expose the bottom portion of the sample vessels108. It is contemplated that the size, shape, and materials comprisingthe enclosed sample holder 1102 and/or the sampling base 1106 may varydepending on the type, size, and shape of the identifier capture device1004 used in the automated sampling/dispensing device, and the type ofsamples to be analyzed (e.g., corrosive, inert, and so forth).

In example implementations, the support surface (e.g., table top 102) ofthe automated sampling/dispensing device can be configured to mate withthe sample holder 1102 (such as shown in FIGS. 33 and 34). For example,the sampling base 1106 can include one or more protrusions 1112 (e.g.,feet). The table top 102 can be keyed with corresponding recesses 1114configured to mate with the protrusions 1112. Alternatively, theprotrusions 1112 can be located on the bottom portion of the enclosedsample holder 1102. By configuring the table top 102 to mate with thesampling base 1106 and/or the enclosed sample holder 1102, the samplingbase 1106 and/or sample holder 1102 is properly oriented for detectionby the sample arm assembly 104 and/or the identifier capture device1004). For example, the front portion or top portion of the sampleholder 1102 is directionally oriented with respect to the sample armassembly 104 and/or the identifier capture device 1004.

In some implementations, the enclosed sample holder 1102 can include asample holder identifier 402 configured to provide dynamic dataassociated with the enclosed sample holder 1102 including, but notlimited to, a unique rack identification (ID), a position of theenclosed sample holder 1102, an orientation of the enclosed sampleholder 1102 (e.g., a standard orientation, a reverse or flippedorientation, etc.), an alignment of the enclosed sample holder 1102, andthe like, as described above. In some implementations, the sample holderidentifier 402 can be located on the sampling base 1106. Alternatively,the sample holder identifier 402 can be located on a top portion, abottom portion, a side portion, a support post portion, or the like, ofthe enclosed sample holder 1102, such that the identifier capture device1004 can recognize the sample holder identifier 402. For example, thesampling base 1106 can include an aperture configured to expose a sampleholder identifier 402 located on a bottom portion of the enclosed sampleholder 1102. In some implementations, the enclosed sample holder 1102can be directionally keyed to fit within the sampling base 1106 in aparticular orientation. By keying the enclosed sample holder 1102, theautomated sampling or dispensing device can detect the orientation ofthe enclosed sample holder 1102 and/or the proper order/configuration ofsample vessels 108 from sample holder identifiers 402 located on thesampling base 1106. For example, a sample holder identifier 402 aincluding identification information that corresponds to a frontorientation of the enclosed sample holder 1102 will correspond to theorientation of both the enclosed sample holder 1102 and the samplingbase 1106.

In some implementations, the identifier capture device 1004 can bepositioned beneath the table top 102, as described above. For example,the autosampler can include a raised surface 1008 configured to besupported by the autosampler table top 102 (such as shown in FIGS. 21Athrough 21C). For instance, in implementations, the raised surface 1008defines gaps 1012 in the surface over which the enclosed sample holders1102 and/or sample vessels 108 having sample holder identifiers 402 andsample identifiers 1002, respectively, positioned on a bottom surfaceare situated. In this manner, the sample holder identifiers 402 and/orsample identifiers 1002 at the base or bottom of the sample vessels 108are accessible to the identifier capture device 1004 when positionedbeneath the raised surface 1008 in the gap 1010 (such as shown in FIG.22). Alternatively, the table top 102, or a portion thereof, may beconstructed from a substantially clear, light transmissive, ortransparent material to expose the bottom portion of the sample vessels108 and/or a bottom portion of the enclosed sample holder 102. In otherimplementations, the identifier capture device 1004 can be positionedabove the table top 102 (e.g., mounted to the sample arm assembly 104).Alternatively, the enclosed sample holders 1102 can be detected bysensors coupled to the table top 102.

Although particular embodiments of this invention have been illustrated,it is apparent that various modifications and embodiments of theinvention may be made by those skilled in the art without departing fromthe scope and spirit of the foregoing disclosure. Accordingly, the scopeof the invention should be limited only by the claims appended hereto.

While the subject matter has been described in language specific tostructural features and/or process operations, it is to be understoodthat the subject matter defined in the appended claims is notnecessarily limited to the specific features or acts described above.Rather, the specific features and acts described above are disclosed asexample forms of implementing the claims.

1.-20. (canceled)
 21. A fluid identification system for an automatedsampling or dispensing device, comprising: a surface structureconfigured to support a fluid container holder configured to receive afluid vessel within an aperture of the fluid container holder, thesurface structure defining a slot extending a length across the surfacestructure; a sample arm assembly including a support extending throughthe slot, the support coupled with a drive assembly configured toprovide translation of the support along the length of the slot, thesample arm assembly configured to support a sample probe configured tobe coupled to the support with at least a portion of the fluid containerholder positioned between the sample probe and the surface structure,the sample probe configured to couple with a tube to receive a fluidfrom the fluid vessel through the sample probe and into the tube; and anidentifier capture device coupled to the support of the sample armassembly with the surface structure configured for positioning betweenthe fluid container holder and the identifier capture device and withthe surface structure configured for positioning between the sampleprobe and the identifier capture device, the identifier capture deviceconfigured to detect at least one of a fluid vessel identifierpositioned on the fluid vessel and a fluid container holder identifierpositioned on the fluid container holder and to generate a data signalin response thereto, the data signal corresponding to at least one of anexpiration status of the fluid within the fluid vessel or anidentification of the fluid container holder.
 22. The fluididentification system as recited in claim 21, wherein the fluid vesselidentifier includes at least one of a barcode or a QR code.
 23. Thefluid identification system as recited in claim 21, wherein the datasignal corresponds to the identification of the fluid container holder.24. The fluid identification system as recited in claim 23, wherein theidentification of the fluid container holder corresponds to at least oneof an orientation of the fluid container holder relative to the surfacestructure, an analysis method associated with the fluid held in fluidvessel in the fluid container holder, an element or species associatedwith fluid held in fluid vessel in the fluid container holder, adilution factor associated with fluid held in fluid vessel in the fluidcontainer holder, a weight associated with fluid held in fluid vessel inthe fluid container holder, or a final volume associated with fluid heldin fluid vessel in the fluid container holder.
 25. The fluididentification system as recited in claim 21, wherein the surfacestructure includes a light transmissive material through which theidentifier capture device detects the fluid vessel identifier.
 26. Thefluid identification system as recited in claim 21, wherein the datasignal corresponds to the expiration status of the fluid, and whereinthe expiration status includes an expiration date associated with thefluid held within the fluid vessel.
 27. The fluid identification systemas recited in claim 26, further including: a controller configured tocompare the expiration date to a current date and to determine that thefluid is expired when the expiration date is the current date or isprior to the current date.
 28. The fluid identification system asrecited in claim 27, wherein the controller is further configured toprovide an alert responsive to determination of expiration of the fluid.29. The fluid identification system as recited in claim 27, wherein thecontroller is further configured to stop operation of the sample armassembly responsive to determination of expiration of the fluid toprevent uptake of the fluid.
 30. The fluid identification system asrecited in claim 21, wherein the identifier capture device is configuredto detect a plurality of fluid container holder identifiers positionedon the fluid container holder.
 31. The fluid identification system asrecited in claim 30, wherein the plurality of fluid container holderidentifiers includes at least two fluid container holder identifiers,each of which correspond to a different orientation of the fluidcontainer holder.
 32. The fluid identification system as recited inclaim 31, wherein the at least two fluid container holder identifiersinclude a first fluid container holder identifier corresponding to astandard orientation of the fluid container holder and a second fluidcontainer holder identifier corresponding to a reverse orientation ofthe fluid container holder.
 33. A fluid identification system for anautomated sampling or dispensing device, comprising: a surface structureconfigured to support a fluid vessel, the surface structure defining aslot extending a length across the surface structure; a sample armassembly including a support extending through the slot, the supportcoupled with a drive assembly configured to provide translation of thesupport along the length of the slot, the support configured to couplewith a sample probe with at least a portion of the fluid vesselpositioned between the sample probe and the surface structure, thesample probe configured to couple with a tube to receive a fluid fromthe fluid vessel through the sample probe and into the tube; and anidentifier capture device coupled to the support of the sample armassembly with the surface structure configured for positioning betweenthe fluid vessel and the identifier capture device and with the surfacestructure configured for positioning between the sample probe and theidentifier capture device, the identifier capture device configured todetect a fluid vessel identifier positioned on the fluid vessel andgenerate a data signal in response thereto, the data signalcorresponding to at least an expiration status of the fluid within thefluid vessel.
 34. The fluid identification system as recited in claim33, wherein the fluid vessel identifier includes at least one of abarcode or a QR code.
 35. The fluid identification system as recited inclaim 33, wherein the surface structure includes a light transmissivematerial through which the identifier capture device is configured todetect the fluid vessel identifier.
 36. The fluid identification systemas recited in claim 33, wherein the expiration status includes anexpiration date associated with the fluid held within the fluid vessel.37. The fluid identification system as recited in claim 36, furtherincluding: a controller configured to compare the expiration date to acurrent date and to determine that the fluid is expired when theexpiration date is the current date or is prior to the current date. 38.The fluid identification system as recited in claim 37, wherein thecontroller is further configured to provide an alert responsive todetermination of expiration of the fluid.
 39. The fluid identificationsystem as recited in claim 37, wherein the controller is furtherconfigured to stop operation of the sample arm assembly responsive todetermination of expiration of the fluid to prevent uptake of the fluid.